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NephroNet

Name: NephroNet
Address: Lawrenceville, GA, US
Telephone: +17704909203
Price range: $

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Contact information, map and directions, contact form, opening hours, services, ratings, photos, videos and announcements from NephroNet, Market Research Consultant, Lawrenceville, GA.

NephroNet is a network of dedicated clinicians, investigators and affiliated sponsors that are collectively committed to advancing patient education, research and the realization of new methods to treat kidney disease.

10/13/2026

We're excited to be heading to ASN 2026 and can't wait to reconnect with familiar faces, make new connections, and share what we've been working on!

📍 Stop by Booth #361 to say hello. We'd love to see you!

10/11/2026

🧠✨ A new nanomedicine approach to calm the immune system.
Researchers have developed cationic lipid-modified PEG-PLGA nanoparticles (CLAN) that precisely deliver dual siRNAs to dendritic cells — reprogramming them to restore immune balance and reduce inflammation in autoimmune disease.
🔬 In an experimental autoimmune encephalomyelitis (EAE) model (a multiple sclerosis equivalent), this approach:
✅ Silenced key immune activation genes (CD40 & LKB1)
✅ Reduced Th1/Th17 inflammation
✅ Promoted regulatory T cell (Treg) activity
✅ Protected spinal cord tissue from damage
💡 Takeaway: CLAN nanoparticles represent a promising tool for retraining the immune system and tackling diseases like multiple sclerosis at their cellular roots.

https://pubmed.ncbi.nlm.nih.gov/41124812/

10/08/2026

Chronic Kidney Disease (CKD) in Indonesia: An Urgent Health Priority
A new multicentre study across 14 primary care centres in Jakarta found that 1 in 7 people with diabetes or hypertension already have CKD — and nearly half are at moderate to very high risk of kidney complications, even when kidney function appears normal.
📊 Key insights:
🔹 CKD prevalence: 14.8%
🔹 Annual eGFR decline: 4.7 mL/min/1.73 m²
🔹 Risk factors: older age, male s*x, albuminuria, haematuria, and cardiovascular disease
🔹 Number needed to screen: 7 patients to find 1 CKD case
💡 Takeaway: Early kidney screening among people with diabetes and hypertension is critical to preventing irreversible kidney damage and improving outcomes.

https://pubmed.ncbi.nlm.nih.gov/41125263/

10/05/2026

⚖️ Weight matters — even in Type 1 diabetes.
A nationwide Japanese study (J-DREAMS) found that overweight adults (BMI ≥ 25 kg/m²) with Type 1 diabetes were more than twice as likely to develop coronary artery disease (CAD) compared to those with lower BMI.
📊 Key findings:
🔹 CAD prevalence: 8.9% in overweight vs. 3.4% in non-overweight
🔹 Overweight linked with neuropathy, nephropathy, hypertension, and dyslipidemia
🔹 Those overweight at age 20 had higher current BMI, HbA1c, and cardiovascular risk
💡 Takeaway: Early and consistent weight management is crucial in Type 1 diabetes to protect heart and kidney health long-term.

https://pubmed.ncbi.nlm.nih.gov/41125203/

10/02/2026

💉 Endothelial health holds the key to understanding diabetic complications.
A new study reveals that lower serum adropin and higher miR-21 expression are strongly linked to endothelial dysfunction in patients with Type 2 diabetes mellitus (T2DM).
🩸 Compared to healthy individuals, people with T2DM — especially those with macrovascular or microvascular complications — showed:
🔹 Significantly lower adropin levels (a peptide that supports metabolic balance)
🔹 Significantly higher miR-21 expression, which correlates with vascular injury
💡 Takeaway: Monitoring adropin and miR-21 may help identify early endothelial damage and predict vascular complications in diabetes.

https://pubmed.ncbi.nlm.nih.gov/41125677/

09/28/2026

🧬 New insights into IgA nephropathy pathogenesis
While B Cell Activating Factor (BAFF) has long been considered a possible driver of IgA overproduction, new evidence suggests otherwise.
In a murine IgA nephropathy model, researchers found that blocking BAFF lowered total immunoglobulin levels but did not affect aberrantly glycosylated IgA, immune complex formation, or glomerular injury.
💡 Takeaway: BAFF inhibition alone may not alter the production of nephritogenic IgA, highlighting the need for more targeted pathways in IgAN therapy.

https://pubmed.ncbi.nlm.nih.gov/41093370/

09/24/2026

🧬 Understanding Glomerulonephritis in Autoimmune Disease
Glomerulonephritis (GN) develops when the immune system mistakenly targets the kidneys — a complex interplay of antibodies, immune cells, and complement activation.
This new review unites findings from biopsy-based pathology, multiomics, and spatial profiling to reveal how lupus nephritis, IgA nephropathy, and ANCA-associated vasculitis share common injury pathways:
💥 Complement activation
🧫 Fc receptor–driven inflammation
🧬 IL-23/IL-17 and type I interferon responses
💡 Takeaway: Though autoimmune GNs begin differently, they converge on shared, targetable mechanisms — paving the way for personalized, pathway-aligned therapy.

https://pubmed.ncbi.nlm.nih.gov/41133475/

09/22/2026

🥼 Metabolic health meets kidney survival.
A new study reveals that a higher Cholesterol-HDL-Glucose (CHG) index, a marker of insulin resistance and metabolic imbalance, is strongly linked to poorer kidney outcomes in patients with IgA nephropathy (IgAN).
📊 In a study of 1,791 biopsy-proven IgAN patients, those with a CHG index > 5.29 had an 84% higher risk of adverse renal outcomes — even after adjusting for other clinical factors.
💡 Takeaway: The CHG index could become a simple, accessible tool to identify patients at risk for faster kidney decline, highlighting the connection between metabolic health and renal survival.

https://pubmed.ncbi.nlm.nih.gov/41103652/

09/17/2026

🧠 New insight into IgA nephropathy and inflammation.
In a real-world study of over 1,000 patients, researchers found that a higher neutrophil-to-lymphocyte ratio (NLR) — an indicator of systemic inflammation — was strongly linked to early kidney function decline (eGFR ≤ 60 mL/min/1.73 m²).
🔬 Elevated NLR correlated with worse clinical features including higher proteinuria, uric acid, and blood pressure — and lower hemoglobin and albumin.
💡 Takeaway: NLR may serve as a simple, accessible biomarker to help predict renal outcomes in IgA nephropathy.

https://pubmed.ncbi.nlm.nih.gov/41131907/

09/14/2026

📈 Redefining prognosis in childhood-onset lupus nephritis (cLN)
A recent study found that tubulointerstitial lesions—especially tubular atrophy—predict kidney function decline more strongly than glomerular changes or activity scores.
The NIH-modified chronicity index (CI) emerged as a reliable prognostic tool, and maintenance therapy with mycophenolate mofetil (MMF) was linked to improved kidney outcomes.
🔍 These findings underscore the value of chronic lesion assessment and optimized therapy to improve long-term outcomes in pediatric lupus nephritis.

https://pubmed.ncbi.nlm.nih.gov/41132094/

Address

Lawrenceville, GA

Opening Hours

Monday	9am - 5pm
Tuesday	9am - 5pm
Wednesday	9am - 5pm
Thursday	9am - 5pm
Friday	9am - 5pm

Telephone

+17704909203

Website

http://www.nephronet.org/

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