06/18/2026
🧬 New Hope for IgA Nephropathy Patients!
The phase 2 ENVISION trial shows that sibeprenlimab, an APRIL-targeting monoclonal antibody, significantly reduced proteinuria in high-risk patients with IgA nephropathy who had already received standard care.
📉 At 12 months:
✔️ Up to 62% reduction in proteinuria with sibeprenlimab
✔️ Slower decline in kidney function (eGFR) compared to placebo
✔️ Similar safety profile between treatment and placebo groups
These results suggest sibeprenlimab may offer a novel, effective therapy for IgA nephropathy. 💡
🔗 Learn more: https://ow.ly/cwTv50WMnJr