Research Group: Developments in Heterocyclic Chemistry

23/02/2018

After a dip in 2016, 2017 brought a two-decade peak in drug approvals. The U.S. Food & Drug Administration gave its green light to 46 new molecular entities, the highest number since 1996. Cancer treatments and drugs for rare diseases continued to command a hefty portion of approvals, and many benef...

28/11/2016

Title: (Short Report) New Strategies for Molecular Diversification of 2-[Aminoalkyl-(1H-1,2,3-triazol-1- yl)]-1,4-naphthoquinones Using Click Chemistry

Authors: Ronaldo N. de Oliveira; Mauro G. da Silva; Moara Targino da Silva; Valentina N. Melo; Wagner O. Valença; Josinete Angela da Paz; Celso A. Camara

DOI number: http://dx.doi.org/10.21577/0103-5053.20160207

Graphical Abstract: Click-chemistry protocol aims to access molecular diversity based on two strategies to obtain scaffolds of 2-amino-alkyl substituted natural and synthetic 1,4-naphthoquinones linked to the 1,2,3-triazole heterocyclic ring.

Find this and other newest papers at: http://jbcs.sbq.org.br/forthcoming_papers

28/11/2016

14/05/2016

06/02/2016

Philip Ball ponders the many reasons that chemists make molecules, and weighs what is lost, and gained, when they don't.