Content GURUDr.Nilesh Kumar Sharma

14/06/2021

By Prof. Nilesh Kumar Sharma: uses of Betel quid ( ) may lead to the tissue microenvironment and a potential contributor of oral .

By Prof. Nilesh Kumar Sharma: uses of Betel quid ( ) may lead to the tissue microenvironment and a potential contributor of ...

25/05/2021

Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of protective antibodies1-7. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals have a significantly lower risk of reinfection8-10. Nonetheless, it has been repo...

16/05/2021

Whether Biological Cells are kinds of MICRO-MACHINE?
Answer Yes:
What about SARS-CoV-2 (CORONAVIRUSES)?
Answer: Yes. SARS-CoV-2 (CORONAVIRUSES) are kinds of NANO-MACHINE driven by NANO-PROTEINS (SPIKE proteins), but lack OWN FUELING SYSTEM. Hence infect HUMAN cells as a HOST for multiplications.
How? Proof?
1. Biological Cells need fuels (e.g Glucose) = Machine needs fuel/power/electricity etc.
2. Biological cells are driven by NANO-PROTEINS= Machine need Wheels for drive/run
3. Biological cells have OWN MECHANICS= Machine is based on Mechanics
4. Biological cells follow the fluid dynamics=Machine is also based fluid dynamics
5. There is a MECHANO-BIOLOGY to understand Cells mechanics= There is MECHANICAL aspects for Machines
6. Biological cells WITHOUT DYNAMICS will become dead/inactive=Machine without FUEL/Dynamics/Motion will become IDLE/Inactive
Many more……….
Message: Nature has created HUMANs with Trillions of such Micro-Machines (Full of Dynamics) that keep humans ALIVE…….Hence, HUMAN is a form of MACHINE……

10/05/2021

तुम बिना मासक पास आये: और corona फलाये........
कया करूँ हाय डर डर सा लगता hai....
तुम मासक पहन के आये तो corona से बचाये..
तुमाहारा mask aur हमारा mask, एक दुसरे को बचाये.....

07/05/2021

A question is baffling what about wave of (e.g., ) at certain interval like months/Years/Century….
A possible clue on the Occurrence of Virus caused at the Interval of ~100 Years….
Here is Possible Answer among many suggested by others…
1. A day on Earth lengthens by around 1.8 milliseconds every 100 years..
2. I was wondering if such changes of 1.8 milliseconds every 100 Years is sensed by Biological cells (Including bacteria and human cells) and non-living nano-cells (~20-120 nm) (Viruses including CORONAVIRUSES).
3. Limited evidence on the existence of BIOLOGICAL CLOCK SYSTEM to sense DAY-NIGHT and Timing in our surrounding by CELLS, but by non-living nano-cells (~20-120 nm) (Viruses including CORONAVIRUSES) is MISSING
4. On interesting note, SARS-CoV-2 -2 protein (2 nano meter) also binds to ACE-2 receptor (2 nm) in a fraction of second.
5. Hence, a strong possibility is there to know the link between changes of 1.8 milliseconds every 100 Years and Biological clock of VIRUSES including and their binding time duration on fraction of seconds upon human cell receptor.
6. Therefore, 1.8 milliseconds every 100 Years and properties of viruses to bind upon human cells may have some relation to activate some of deadly viruses across the evolutionary time.
7. Most of these DEADLY VIRUSES are of RNA genetic material and that also proves the ongoing war between RNA world led by VIRUSES like CORONAVIRUSES and DNA world led by HUMANs and other organisms on this earth.
8. Second question on the WAVE pattern of invective viruses, some time rises and falls in terms of number of infected persons across the month and years. I predict that NANO-CELLS non-living viruses have mechanisms of SENSING environment by staying within the human body environment.
9. By doing this, whether in case of SARS-CoV-2 viruses are able to sense their total virus particles generated in this environment by multiplying in human hosts. By reaching to a certain number in human body system and a number of persons that multiply these viruses, viruses sense the number and creates a pattern of growth like a WAVE PATTERN. By doing this wave pattern of growth and multiplication, a significant number of human populations are infected.
10. In conclusion, this tug of war between RNA world (CORONAVIRUSES) and DNA world (HUMANS) is in existence since millions of years and will exist for thousands of years.
Keep using MASKS and be safe.

26/04/2021

Whether SARS-CoV-2 virus persistent infection among human populations may modulate key Gene for the shape of facial structures including nose shape etc.,? Because earlier viruses had brought changes to developmental Genes.

25/04/2021

Points for Social Awareness and Need To Know....
Currently...Problems regarding "LOG ON" and "LOG OFF"............

So what are "LOG ON" and "LOG OFF"?????.....................
Liquid Oxygen Gas (LOG) ON and Liquid Oxygen Gas (LOG) OFF , we are aware through news/media that Liquid Oxygen Gas (LOG) is the need of the time...
Some time, we are blaming Government and Administration for Liquid Oxygen Gas (LOG), BUT should we understand at the society level, from where Liquid Oxygen Gas (LOG) will come and manufactured...
Please read:
One liter of Liquid Oxygen Gas (LOG)= 860 liter of Oxygen in gas form form=860 Liter X 5 (Because only ~20% of Oxygen in Air)=4300 Liter of Air in our surrounding.
We can understand that 4300 Liter of Air is used for preparing One liter of Liquid Oxygen Gas (LOG). This is not an easy task....
As an Individual/Society, how we contribute to create a liter of Oxygen by Planting a Tree/Plants/Flowers or any such Thing...Please ask our-self and then accept our own mistake.....
Like Liquid Oxygen Gas (LOG), Liquid Petroleum Gas (LPG), Liquid Natural Gas (LNG), all are limited by NATURE......and will get exhausted in ONE DAY........
Then, key message is that please start PLANTING Trees/Plants/Flowers so that OUR air will get replenished in future to MANUFACTURE ONE LITER OF Liquid Oxygen Gas (LOG) from 4300 Liter of AIR.......
We are witnessing and in future, we should be ready for "LOG ON" and "LOG OFF"......Even WAR/Conflicts at Society, Country and global Level is HIGHLY PREDICTABLE in TIME to come.
Please keep using masks and be safe.

23/04/2021

Interesting and I was wondering that why all humans have to take VITAMIN C during COVID-19?

Why not VITAMIN B5 and other vitamins?

I found interesting data:

Vitamin C in WHEAT= 0 mg
Vitamin C in RICE= 0 mg
Vitamin C in milk= 0 mg
Vitamin C in animals foods like meat= 0 mg
Only selected plant foods= Few mg of Vitamin C

Important to note, NATURE has deleted Gene from Humans that can synthesize OWN Vitamin C..............

On the other hand, Vitamin B5 and others are present in ALL Foods from plants and Animals.

This means Nature has played TRICK with humans..................................

by NOT allowing for becoming a super-ORGANISM and made an HUNTER for Vitamin C from the Nature........during COVID19.

I think time has come to go FOR GENETICALLY ENGINEERED WHEAT/RICE....................finally HUMANS with VITAMIN C gene

17/04/2021

A proposition on ​ ​/Cell Mines/Tissue Mines within the human body: A clue for . A take home message is to convince our-self to contain our life-style and environments so that Sleeping Tissue mines should not turn into Tumor.

By Prof. Nilesh Kumar Sharma: A proposition on /Cell Mines/Tissue Mines within the human body: A clue for

16/04/2021

A Small video by Prof. Sharma on '2D Cell Culture To 3D Cell Culture to 4D To essentially 5D Cell Culture is the need of the time to REAL TISSUE MICROENVIRONMENT

Prof. Nilesh Kumar Sharma: A model on (Dimension) to mimic microenvironment"

10/04/2021

Interesting, a Choice Based Chemical Selection (CBCS) is crucial for tumor microenvironment (TME) to be destructive and deadly.
An analogy is made with Choice Based Credit System (CBCS) in our curriculum/Education system.
If we try to understand Choice Based Chemical Selection (CBCS), tumors have selection and choices of chemicals such as Glucose, various amino acids and many more to be aggressive, adapt for evasion and survive during stress/drug insults etc.,
What is the lesson to learn? Cancer cells have better equipped Choice Based Chemical Selection (CBCS) compared to normal cells that allow them to be destructive in nature.

Cancer cells characteristically consume glucose through Warburg metabolism1, a process that forms the basis of tumour imaging by positron emission tomography (PET). Tumour-infiltrating immune cells also rely on glucose, and impaired immune cell metabolism in the tumour microenvironment (T...